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  • Desvaux E, Hemon P, Soret P, Le Dantec C, Chatzis L, Cornec D, Devauchelle-Pensec V, Beretta L, Vigone B, Pers J-O, Saraux A, PRECISESADS clinical consortium, Elouej S, Duguet F, Laigle L, Poirier N, Moingeon P, Bretin S, Pers J-O. High-content multimodal analysis supports the IL-7/IL-7 receptor axis as a relevant therapeutic target in primary Sjögren's syndrome. Journal of Autoimmunity. 2023:103147. doi: 10.1016/j.jaut.2023.103147.

 

  • Keller KK, Mukhtyar CB, Nielsen AW, Hemmig AK, Mackie SL, Sattui SE, Hauge EM, Dua A, Helliwell T, Neill L, Blockmans D, Devauchelle-Pensec V, Hayes E, Venneboer AJ, Monti S, Ponte C, De Miguel E, Matza M, Warrington KJ, Byram K, Yaseen K, Peoples C, Putman M, Lally L, Finikiotis M, Appenzeller S, Caramori U, Toro-Gutiérrez CE, Backhouse E, Oviedo MCG, Pimentel-Quiroz VR, Keen HI, Owen CE, Daikeler T, de Thurah A, Schmidt WA, Brouwer E, Dejaco C. Recommendations for early referral of individuals with suspected polymyalgia rheumatica: an initiative from the international giant cell arteritis and polymyalgia rheumatica study group. Ann Rheum Dis. 2023 Dec 1:ard-2023-225134. doi: 10.1136/ard-2023-225134.

 

  • Rouviere B, Le Dantec C, Foulquier N, Cornec D, Pers JO, De Moreuil C, Hillion S. Hétérogénéité des mécanismes auto-immuns impliques dans la sclérodermie systémique. La Revue de Médecine Interne. 2023;44:A383-A4. doi: 10.1016/j.revmed.2023.10.094

 

  • Mariniello M, Schiano G, Yoshifuji A, Gillion V, Sayer JA, Jouret F, Genkyst Study Group, Le Meur Y, Cornec-Le Gall E, Olinger EG, Devuyst O, Uromodulin Processing in DNAJB11-kidney Disease, Kidney International (2023), doi: 10.1016/j.kint.2023.11.008

 

  • Saraux A, Le Henaff C, Dernis E, Carvajal-Alegria G, Tison A, Quere B, Petit H, Felten R, Jousse-Joulin S, Guellec D, Marhadour T, Kervarrec P, Cornec D, Querellou S, Nowak E, Souki A, Devauchelle-Pensec V. Abatacept in early polymyalgia rheumatica (ALORS): a proof-of-concept, randomised, placebo-controlled, parallel-group trial. The Lancet Rheumatology. 2023;5(12):e728-e35. doi: 10.1016/S2665-9913(23)00246-1

The UMR1227 'B Lymphocytes and Autoimmunity' brings together several clinical entities around the immunology laboratory.

Rheumatology, haematology, nephorology and odontology for a scientific project articulated around two main complementary and interconnected axes: an axis dedicated to the understanding of the mechanisms that govern the functional orientation of B cells in autoimmunity, and a translational axis aiming at developing new tools to improve the efficiency of B-cell targeting immunotherapies, while working on a better stratification of patients, a better understanding of the mode of action of these therapies, and the development of these therapies and innovative therapeutic strategies.

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