Linear diattenuation imaging of biological tissues with near infrared Mueller scanning microscopy. Dubreuil, M., Tissier, F., Rivet, S., & Le Grand, Y. (2021). Biomedical optics express, 12(1), 41-54.
Evidence of a hormonal reshuffle in the cecal metabolome fingerprint of a strain of rats resistant to decompression sickness. Vallee, N., Dugrenot, E., Desruelle, A. V., Tardivel, C., Martin, J. C., Guernec, A., ... & Guerrero, F. (2021). Scientific reports, 11(1), 1-12.
Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons. Pierre O, Fouchard M, Le Goux N, Buscaglia P, Leschiera R, Lewis RJ, Mignen O, Fluhr JW, Misery L, Le Garrec R. Mar Drugs. 2021 Jul 6;19(7):387. doi: 10.3390/md19070387.
Poly- and Oligosaccharide Ulva sp. Fractions from Enzyme-Assisted Extraction Modulate the Metabolism of Extracellular Matrix in Human Skin Fibroblasts: Potential in Anti-Aging Dermo-Cosmetic Applications. Fournière M, Bedoux G, Lebonvallet N, Leschiera R, Le Goff-Pain C, Bourgougnon N, Latire T. Mar Drugs. 2021 Mar 17;19(3):156. doi: 10.3390/md19030156.
The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis. Burgos M, Philippe R, Antigny F, Buscaglia P, Masson E, Mukherjee S, Dubar P, Le Maréchal C, Campeotto F, Lebonvallet N, Frieden M, Llopis J, Domingo B, Stathopulos PB, Ikura M, Brooks W, Guida W, Chen JM, Ferec C, Capiod T, Mignen O. J Cell Sci. 2021 Feb 10;134(3):jcs244012. doi: 10.1242/jcs.244012.
In Vitro Differentiation of Human Skin-Derived Cells into Functional Sensory Neurons-Like. Bataille A, Leschiera R, L'Hérondelle K, Pennec JP, Le Goux N, Mignen O, Sakka M, Plée-Gautier E, Brun C, Oddos T, Carré JL, Misery L, Lebonvallet N. Cells. 2020 Apr 17;9(4):1000. doi: 10.3390/cells9041000.
TGF-β pathway inhibition protects the diaphragm from sepsis-induced wasting and weakness in rat. Jude, B., Tissier, F., Dubourg, A., Droguet, M., Castel, T., Léon, K., ... & Pennec, J. P. (2020). Shock, 53(6), 772-778.
Exercise training changes mitochondrial function and its vulnerability to reactive oxygen species exposure differently in male and female silver European eels. Farhat, F., Simon, B., Amérand, A., Devaux, J., Belhomme, M., Calves, P., & Moisan, C. (2020). Environmental Biology of Fishes, 103(4).
Multiexcitonic broad band emission enhanced by Resonant energy Transfer in a new Two-dimensional Organic Inorganic Perovskite: (C3H8N6)PbCl4. O. Medhioub, A. Samet, H. Barkaoui, S. Triki, Y. Abid, J. Phys. Chem. C 2020, 124, 20359–20366.
Physiological characteristics associated with increased resistance to decompression sickness in male and female rats. Lautridou, J., Dugrenot, E., Amérand, A., Guernec, A., Pichavant-Rafini, K., Goanvec, C., ... & Guerrero, F. (2020). Journal of Applied Physiology, 129(3), 612-625.
Identification and Characterization of a New Type III Polyketide Synthase from a Marine Yeast, Naganishia uzbekistanensis. Mar Drugs. 2020 Dec 11;18(12):637. doi: 10.3390/md18120637
Keratinocytes Communicate with Sensory Neurons via Synaptic-like Contacts. Talagas M, Lebonvallet N, Leschiera R, Sinquin G, Elies P, Haftek M, Pennec JP, Ressnikoff D, La Padula V, Le Garrec R, L'herondelle K, Mignen O, Le Pottier L, Kerfant N, Reux A, Marcorelles P, Misery L. Ann Neurol. 2020 Dec;88(6):1205-1219. doi: 10.1002/ana.25912. Epub 2020 Oct 10.
In Vitro Differentiation of Human Skin-Derived Cells into Functional Sensory Neurons-Like. Bataille A, Leschiera R, L'Hérondelle K, Pennec JP, Le Goux N, Mignen O, Sakka M, Plée-Gautier E, Brun C, Oddos T, Carré JL, Misery L, Lebonvallet N. Cells. 2020 Apr 17;9(4):1000. doi: 10.3390/cells9041000.
Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling. Pierre O, Fouchard M, Buscaglia P, Le Goux N, Leschiera R, Mignen O, Fluhr JW, Misery L, Le Garrec R. Cells. 2020 Dec 17;9(12):2704. doi: 10.3390/cells9122704.
Neurological Disturbances of Ciguatera Poisoning: Clinical Features and Pathophysiological Basis. L'Herondelle K, Talagas M, Mignen O, Misery L, Le Garrec R. Cells. 2020
PAR2, Keratinocytes, and Cathepsin S Mediate the Sensory Effects of Ciguatoxins Responsible for Ciguatera Poisoning. L'Herondelle K, Pierre O, Fouyet S, Leschiera R, Le Gall-Ianotto C, Philippe R, Buscaglia P, Mignen O, Talagas M, Lewis RJ, Michel L, Misery L, Le Garrec R. J Invest Dermatol. 2021 Mar;141(3):648-658.e3. doi: 10.1016/j.jid.2020.07.020. Epub 2020 Aug 13.
Endothelial function may be enhanced in the cutaneous microcirculation after a single air dive. Guerrero, F., Lambrechts, K., Wang, Q., Mazur, A., Théron, M., & Marroni, A. (2020). Diving and Hyperbaric Medicine, 50(3), 214-219.
Cardiotoxicity and myocardial infarction‐associated DNA damage induced by thiamethoxam in vitro and in vivo: Protective role of Trigonella foenum‐graecum seed‐derived polysaccharide. Feki, A., Ben Saad, H., Bkhairia, I., Ktari, N., Naifar, M., Boudawara, O., ... & Ben Amara, I. (2019). Environmental toxicology, 34(3), 271-282.
Antibacterial and transfection activities of nebulized formulations incorporating long n-alkyl chain silver N-heterocyclic carbene complexes Mottais, M. Berchel, T. Le Gall, Y. Sibiril, F. d’Arbonneau, V. Laurent, P.A. Jaffrès, T. Montier ; Inter. J. Pharm., 2019, 567, 118500.
Aerosol delivery to the airways using cationic lipid nanocomplexes in a perspective of cystic fibrosis treatment. M. Berchel, P.A. Jaffrès, T. Le Gall, T. Montier. ACS Symposium series, 2019, 1309, Chapter 2, p35-58. DOI : 10.1021/bk-2019-1309.ch002.
Resonantly enhanced white-light emission involving energy and charge transfer in one-dimensional hybrid material: (ABT)2[PbBr3]", A. Samet, S. Triki, Y. Abid, J. Phys. Chem. C 2019, 123, 6213–6219.
Negative Thermal Quenching of Efficient White-Light Emission in a 1D Ladder-Like Organic/Inorganic Hybrid Material. H. Barkaoui, H. Abid, S. Zelewski, J. Urban, M. Baranowski, A. Mlayah, S. Triki, P. Plochocka, Y. Abid, Adv. Opt. Mater. 2019, 7, 1900763.
Blue Emission From Charge Transfer Excitons in Hybrid Organic-Inorganic Quantum Wires: (ABT)[PbCl3]. O. Medhioub, H. Barkaoui, A. Samet, S. Pillet, S. Triki, and Y. Abid, J. Phys. Chem. C 2019, 123, 26547-26553.
Thiol-ene click reaction to construct the lipid chains of cationic amphiphiles: physico-chemical behaviour and application for gene delivery A. Bouraoui, M. Berchel, R. Ghanem, V. Vié, G. Paboeuf, L. Deschamps, O. Lozach, T. Le Gall, T. Montier, P.A. Jaffrès Org. Biomol. Chem, 2019, 17, 3609-3616.
Lipid-Based Quaternary Ammonium Sophorolipid Amphiphiles with Antimicrobial and Transfection Activities. E. I. P. Delbeke, J. Everaert, O. Lozach, T. Le Gall, M. Berchel, T. Montier, P.A. Jaffrès, P. Rigole, T. Coenye, M. Brennich, N. Baccile, S. L. K. W. Roelants, W. Soetaert, I. N. A. Van Bogaert, K. M. Van Geem, C. V. Stevens ChemSusChem, 2019, 12, 3642-3653.
Bis-thioether containing lipid chains in cationic amphiphiles: physicochemical properties and application for gene delivery A. Bouraoui, R. Ghanem, M. Berchel, V. Vié, Y. Le Guen, G. Paboeuf, L. Deschamps, T. Le Gall, T. Montier, P.A. Jaffrès ChemPhysChem, 2019, 20, 2187-2194.
Antibacterial effect and DNA delivery using a combination of an arsonium-containing lipophosphoramide with an N-heterocyclic carbene-silver complex – Potential benefits for cystic fibrosis lung gene therapy. A. Mottais, M. Berchel, Y. Sibiril, V. Laurent, D. Gill, S. Hyde, P.A. Jaffrès, T. Montier, T. Le Gall. Inter. J. Pharm., 2018, 536, 29-41.
Synthesis and Biological Evaluation of Bolaamphiphilic Sophorolipids E. I. P. Delbeke, J. Everaert, O. Lozach, T. Le Gall, M. Berchel, T. Montier, P.A. Jaffrès, P. Rigole, T. Coenye, M. Brennich, N. Baccile, S. L. K. W. Roelants, W. Soetaert, I. N. A. Van Bogaert, K. M. Van Geem, C. V. Stevens ACS Sustainable Chem. Eng. 2018, 6, 8992−9005.
A new tool to test active ingredient using lactic acid in vitro, a help to understand cellular mechanism involved in stinging test: An example using a bacterial polysaccharide (Fucogel® ). Sakka M, Leschiera R, Le Gall-Ianotto C, Gouin O, L'herondelle K, Buscaglia P, Mignen O, Philbé JL, Saguet T, Carré JL, Misery L, Lebonvallet N. Exp Dermatol. 2018 Mar;27(3):238-244. doi: 10.1111/exd.13489. Epub 2018 Feb 7. PMID: 29280518
Cationic amphiphiles producing hexagonal aggregates: Physico-chemical characterization and application to gene delivery. A. Bouraoui, R. Ghanem, M. Berchel, L. Deschamps, V. Vié, G. Paboeuf, T. Le Gall, T. Montier, P.A. Jaffrès Org. Biomol. Chem., 2020, 18, 337-345.
Major Role for TRPV1 and InsP3R in PAR2-Elicited Inflammatory Mediator Production in Differentiated Human Keratinocytes. Gouin O, L'Herondelle K, Buscaglia P, Le Gall-Ianotto C, Philippe R, Legoux N, Mignen O, Buhé V, Leschiera R, Sakka M, Kerfant N, Carré JL, Le Garrec R, Lefeuvre L, Lebonvallet N, Misery L. J Invest Dermatol. 2018 Jul;138(7):1564-1572. doi: 10.1016/j.jid.2018.01.034. Epub 2018 Feb 17. PMID: 29458120
A new tool to test active ingredient using lactic acid in vitro, a help to understand cellular mechanism involved in stinging test: An example using a bacterial polysaccharide (Fucogel® ). Sakka M, Leschiera R, Le Gall-Ianotto C, Gouin O, L'herondelle K, Buscaglia P, Mignen O, Philbé JL, Saguet T, Carré JL, Misery L, Lebonvallet N. Exp Dermatol. 2018 Mar;27(3):238-244. doi: 10.1111/exd.13489. Epub 2018 Feb 7. PMID: 29280518
Major Role for TRPV1 and InsP3R in PAR2-Elicited Inflammatory Mediator Production in Differentiated Human Keratinocytes. Gouin O, L'Herondelle K, Buscaglia P, Le Gall-Ianotto C, Philippe R, Legoux N, Mignen O, Buhé V, Leschiera R, Sakka M, Kerfant N, Carré JL, Le Garrec R, Lefeuvre L, Lebonvallet N, Misery L. J Invest Dermatol. 2018 Jul;138(7):1564-1572. doi: 10.1016/j.jid.2018.01.034. Epub 2018 Feb 17. PMID: 29458120
Hypolipidemic and cardioprotective effects of Ulva lactuca ethanolic extract in hypercholesterolemic mice. Archives of physiology and biochemistry, 124(4), 313-325.Kammoun, I., Ben Salah, H., Ben Saad, H., Cherif, B., Droguet, M., Magné, C., ... & Ben Amara, I. (2018).
A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations. Hum Mol Genet. 27(12): 2138-2153. Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaëc N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg H, Chelly J, Humeau Y, Friocourt G*, Hérault Y*. (2018).
Basal ganglia involvement in ARX gene mutated patients: the reason for very specific grasping in ARX mutated patients? Neuroimage: Clinical. 19, 454-465. Curie A*, Friocourt G*, des Portes V, Roy A, Nazir T, Brun A, Cheylus A, Marcorelles P, Retzepi K, Maleki N, Bussy G, Paulignan Y, Reboul A, Ibarrola D, Kong J, Hadjikhani N, Laquerrière A and Gollub R. (2018).
Polarization-resolved second harmonic microscopy of skeletal muscle in sepsis. Biomedical optics express, 9(12), 6350-6358. Dubreuil, M., Tissier, F., Le Roy, L., Pennec, J. P., Rivet, S., Giroux-Metges, M. A., & Le Grand, Y. (2018).
Long-term atorvastatin treatment decreases heart maximal oxygen consumption and its vulnerability to in vitro oxidative stress in Watanabe heritable hyperlipidemic rabbit. Tissier, F., Farhat, F., Philouze, C., Desfontis, J. C., Didier, R., Gilard, M., ... & Amérand, A. (2018). Canadian journal of physiology and pharmacology, 96(11), 1112-1118.
Five-Year Clinical Outcome and Valve Durability After Transcatheter Aortic Valve Replacement in High-Risk Patients: FRANCE-2 Registry. Doisy, V., Lognone, T., Gommeaux, A., Claudel, J. P., Bourlon, F., Bertrand, B., ... & Ohlmann, P. (2018). Circulation, 138(23), 2597-2607.
The linker between the two fatty acid chains of the cationic and helper lipids plays a critical role in the morphology of liposomes and transfection efficiency Mevel, M.; Peuziat, P.; Dallet, L.; Chatin, B.; Haudebourg, T.; Colombani, T.; Lambert, O.; Berchel, M.; Le Gall, T.; Montier, T.; Jaffrès, P.A.; Lehn, P.; Pitard, B. J. Gene Med, 2016, 18, 3-15.
The alkyl-lipid Ohmline modifies the anti-EGFR mAbs action through the control of calcium signaling and Akt in colon cancer cells. M. Guéguinou, T. Harnois, D. Crottes, N. Deliot, A. Gambade, A. Chantôme, J.P. Haelters, P.A. Jaffrès, ML. Jourdan, G. Weber, P. Bougnoux, O. Mignen, N. Bourmeyster, B. Constantin, T. Lecomte, C. Vandier, M. Potier-Cartereau. Oncotarget, 2016, 7, 36168-36184.
Lipophosphoramidate-based bipolar amphiphiles: their syntheses and transfection propertie M. Berchel, T. Le Gall, O. Lozach, J.P. Haelters, T. Montier, P.A. Jaffrès Org. Biomol. Chem., 2016, 14, 2846-53. Evaluation of the transfection efficacies of quaternary ammonium prepared from sophorolipid E. I. P. Delbeke, O. Lozach, T. Le Gall, M. Berchel, T. Montier, P.-A. Jaffrès, K.M. Van Geemg, C. V. Stevens. Org. Biomol. Chem., 2016, 14, 3744-3751.
Thiol-ene click reaction applied to cationic amphiphiles: impacts on supramolecular packing and gene transfection properties. D. Afonso, T. Le Gall, H. Couthon-Gourvès, A. Grélard, S. Prakash, M. Berchel, N. Kervarec, E.J. Dufourc, T. Montier, P.A. JaffrèsSoft Matter, 2016, 12, 4516 – 4520.
Cationic dialkylarylphosphates: a new family of bio-inspired cationic lipids for gene delivery. S. S. Le Corre, N. Belmadi, M. Berchel, T. Le Gall, J.P. Haelters, P. Lehn, T. Montier, P.A. Jaffrès. Org. Biomol. Chem., 2015, 13, 1122-1132.
Lipophosphoramidates containing cationic hydroxylated polar head group for improving gene delivery. Berchel, M.; Le Gall, T.; Haelters, J.P.; Lehn, P.; Montier, T.; Jaffrès, P.A. Mol. Pharm., 2015, 12, 1902-1910.
Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration Belmani, N.; Midoux, P.; Pichon, C.; Loyer, P.; Passirani, C.; Le Gall, T.; Jaffrès, P.A.; Lehn, P.; Montier, T. Biotechnol. J., 2015, 10,1370–1389.
Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure M.F. Lindberg, T. Le Gall, N. Carmoy, M. Berchel, S.C. Hyde, D.R. Gill, P.A. Jaffrès, P. Lehn, T. Montier, Biomaterials, 2015, 59, 1-11.
Evaluation of New Fluorescent Lipophosphoramidates for Gene Transfer and Biodistribution Studies after Systemic Administration Nawal Belmadi, Mathieu Berchel, Caroline Denis, Wilfried Berthe, Yann Sibiril, Tony Le Gall, Jean-Pierre Haelters, Paul-Alain Jaffrès, Tristan Monti Inter. J. Mol. Sci., 2015, 16, 26055–26076.