Patrice Hémon

patrice-hemon

Patrice Hémon

IGR UBO
hemonpatrice(at)gmail.com
+33(0)2 29 02 01 55

Hemon P, Jean-Louis F, Ramgolam K, Brignone C, Viguier M, Bachelez H, Triebel F, Charron D, Aoudjit F, Al-Daccak R, Michel L. MHC class II engagement by its ligand LAG-3 (CD223) contributes to melanoma resistance to apoptosis. J Immunol. 2011 May 1;186(9):5173-83.

 

Taflin C, Favier B, Baudhuin J, Savenay A, Hemon P, Bensussan A, Charron D, Glotz D, Mooney N. Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2891-6.

 

Le Buanec H, Gougeon ML, Mathian A, Lebon P, Dupont JM, Peltre G, Hemon P, Schmid M, Bizzini B, Künding T, Burny A, Bensussan A, Amoura Z, Gallo RC, Zagury D. IFN-α and CD46 stimulation are associated with active lupus and skew natural T regulatory cell differentiation to type 1 regulatory T (Tr1) cells. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18995-9000.

 

Zeina El Ali, Cédric Gerbeix, Patrice Hemon, Philipp R. Esser, Stefan F. Martin, Marc Pallardy & Saadia Kerdine-Römer. Allergic skin inflammation induced by chemical sensitizers is controlled by the transcription factor nrf2. Toxicol Sci. 2013 Jul;134(1):39-48.

 

Alexandre Bignon, Françoise Gaudin, Patrice Hemon, Hugo Tharinger, Pius Loetscher, Michel Peuchmaur, Dominique Berrebi and Karl Balabanian. Pivotal role of Ccr1 in murine lupus nephritis. J Immunol. 2014 Feb 1;192(3):886-96.

 

Nicolas Dulphy, Guylaine Henry, Patrice Hemon, Zena Khaznadar, Hervé Dombret, Nicolas Boissel, Armand Bensussan, Antoine Toubert. Contribution of CD39 to the immunosuppressive microenvironment of acute myeloid leukaemia at diagnosis. British Journal of Haematology. Jun ;165(5):722-5. doi: 10.1111 Epub 2014 Feb 12.

 

Boujedidi H, Robert O, Bignon A, Cassard-Doulcier AM, Renoud ML, Gary-Gouy H, Hemon P, Tharinger H, Prévot S, Bachelerie F, Naveau S, Emilie D, Balabanian K, Perlemuter G. CXCR4 dysfunction in non-alcoholic steatohepatitis in mice and patients. Clin Sci (Lond). 2014 Jul 30.

 

Bastid J, Regairaz A, Bonnefoy N, Déjou C, Giustiniani J, Laheurte C, Cochaud S, Laprevotte E, Funck-Brentano E,Hemon P, Gros L, Bec N, Larroque C, Alberici G, Bensussan A, Eliaou JF. Inhibition of CD39 enzymatic function at the surface of tumor cells alleviates their immunosuppressive activity.Cancer Immunology Research, 2015 Mar;3(3):254-65.

 

Robert O, Boujedidi H, Bigorgne A, Ferrere G, Voican CS, Vettorazzi S, Tuckermann JP, Bouchet-Delbos L, Tran T, Hemon P, Puchois V, Dagher I, Douard R, Gaudin F, Gary-Gouy H, Capel F, Durand-Gasselin I, Prévot S, Rousset S, Naveau S, Godot V, Emilie D, Lombès M, Perlemuter G, Cassard AM. Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice. J Hepatol. 2015 Nov 27. pii: S0168-8278(15)00781-3.


Marjolaine Debant, Patrice Hemon, Christophe Brigaudeau, Yves Renaudineau and Olivier Mignen. Calcium signaling and cell fate: how Ca2+ signals may contribute to wrong decisions for Chronic Lymphocytic Leukemic B lymphocyte outcome? Int J Dev Biol. 2015;59(7-9):379-89.

 

Meuris F, Gaudin F, Aknin ML, Hémon P, Berrebi D, Bachelerie F. Symptomatic Improvement in Human Papillomavirus-Induced Epithelial Neoplasia by Specific Targeting of the CXCR4 Chemokine Receptor. J Invest Dermatol. 2016 Feb;136(2):473-80. doi: 10.1016/j.jid.2015.11.004.

 

Pionnier N, Brotin E, Karadjian G, Hemon P, Gaudin-Nomé F, Vallarino-Lhermitte N, Nieguitsila A, Fercoq F, Aknin ML, Marin-Esteban V, Chollet-Martin S, Schlecht-Louf G, Bachelerie F, Martin C. Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae. PLoS Negl Trop Dis. 2016 Apr 25;10(4):e0004605.

 

Biajoux V, Natt J, Freitas C, Alouche N, Sacquin A, Hemon P, Gaudin F, Fazilleau N, Espéli M, Balabanian K. Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization. Cell Rep. 2016 Sep 27;17(1):193-205. doi: 10.1016/j.celrep.2016.08.068.

 

Hemon P, Renaudineau Y, Debant M, Le Goux N, Mukherjee S, Brooks W, Mignen O. Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity. Clin Rev Allergy Immunol. 2017 May 13 doi: 10.1007/s12016-017-8607-6

 

De Groof A, Hémon P, Mignen O, Pers JO, Wakeland EK, Renaudineau Y, Lauwerys BR. Dysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus. Clin Rev Allergy Immunol. 2017 May 13. doi: 10.1007/s12016-017-8605-8.

 

Jaracz-Ros A, Hémon P, Krzysiek R, Bachelerie F, Schlecht-Louf G, Gary-Gouy H. OMIP-048 MC: Quantification of calcium sensors and channels expression in lymphocyte subsets by mass cytometry. Cytometry A. 2018 Jul;93(7):681-684. doi: 10.1002/cyto.a.23504.

 

Debant M, Burgos M, Hemon P, Buscaglia P, Fali T, Melayah S, Le Goux N, Vandier C, Potier-Cartereau M, Pers JO, Tempescul A, Berthou C, Bagacean C, Mignen O, Renaudineau Y. STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia. J Immunother Cancer. 2019 Apr 23;7(1):111. doi: 10.1186/s40425-019-0591-3.

 

Elaldi R, Hemon P, Petti L, Cosson E, Desrues B, Sudaka A, Poissonnet G, Van Obberghen-Schilling E, Pers JO, Braud VM, Anjuère F, Meghraoui-Kheddar A. High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture. Front Immunol. 2021 Apr 16;12:666233. doi: 10.3389/fimmu.2021.666233. eCollection 2021.